Circular single-stranded DNA viruses represent a diverse group of pathogens that possess a covalently closed, circular single-stranded DNA genome. Their small genomes belie a sophisticated replication strategy, typically involving rolling circle mechanisms ...

Extrachromosomal DNAs (ecDNAs) are circular DNA structures located in the nuclei of cells outside chromosomes. They were originally discovered in chromosome spreads of cells obtained from embryonal tumors in the 1960s and were called “double minutes ...

Before Watson and Crick basked in Nobel glory, before The Double Helix mythologized their genius, there was the photo. Photo 51 — crisp, clear, and groundbreaking — captured by Dr. Rosalind Franklin, the crystallographer whose name is often footnoted ...