When neuroscientists analyzed the exact properties of nerve connections in the brain, they made a startling observation: At a key connection, or synapse, messages are sent against the usual stream of ...

Researchers at Fujita Health University and the Tokyo Metropolitan Institute of Medical Science have uncovered a previously ...

A new study reveals how young synapses gradually mature to send chemical signals correctly — a process that can take days and depends on neural activity.

Nervous system functions, from motion to perception to cognition, depend on the active zones of neural circuit connections ...

(1) A nerve impulse arrives. (2) This causes calcium ion channels to open, resulting in an influx of calcium ions in the terminal. (3) This causes synaptic vesicles to fuse with the terminal membrane, ...

How do people think, feel, remember, and move? These processes rely on synaptic transmission, where chemical signals are passed between nerve cells using molecular structures called vesicles.

The synaptotagmin protein family has been studied by neuroscientists for decades. However, most isoforms lack well-defined functions. Now, researchers have identified a crucial, presynaptic role for ...

Transmission electron microscopy reveals the architecture of cells at nanometer resolution, but chemical fixation severely warps their native structure. The true ultrastructure of cells can be ...

Boost Neuroscience is a “stealth” biotech company that has developed a proprietary synapse network platform based on the work of Nobel Laureate Dr. Thomas Südhof, M.D. Boost was spun out of Stanford ...