Genes and alleles are essential to basic genetics, but what are the differences between them? In this guide, we compare genes and alleles and provide simple definitions and examples for both. Genes ...

Large-scale sequencing in the 1000 Genomes Project has revealed multitudes of single nucleotide variants (SNVs). Here, we provide insights into the functional effect of these variants using ...

Allele frequency is a measure of the relative frequency of an allele on a genetic locus in a population. Usually it is expressed as a proportion or a percentage. In population genetics, allele ...

In general, humans have the same genes. A number of genes are varied. These control our physical traits and health. Each variation is called an allele. You inherit two alleles for each gene. One comes ...

We discuss two formulations of the infinitely-many-neutral-alleles diffusion model that can be used to study the ages of alleles. The first one, which was introduced elsewhere, assumes values in the ...

Your genes are made of DNA. This DNA provides instructions, which determines traits like your hair color and blood type. There are different versions of genes. Each ...

Selection in a finite population (N) under the general two-allele one-locus model revealed the following. 1. When the favorable allele is recessive, the expected time to fixation is accelerated as ...

Evaluating next-generation sequencing (NGS) data and associated clinical records of head and neck squamous cell carcinoma (HNSCC) patients from several institutions, made available through The Cancer ...

Someone who is homozygous (ff) for the recessive allele will develop cystic fibrosis. Someone who is heterozygous (Ff) or homozygous (FF) for the dominant allele will not develop cystic fibrosis. In ...