Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The bioenergetic requirements of muscle stem ...

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production.

The glycocalyx surrounds each cell in the human body like a coat. This complex sugar layer plays a key role in the progression of numerous diseases, such as cancer and autoimmune diseases. The ...

Muscle function and composition are important indicators of age-related health. However, current assessment methods are often complex and expensive, making the early detection of related problems ...

A previously unknown structure discovered in our cells could pave the way toward new treatments for various genetic disorders. The existence of the organelle—which has been dubbed the "hemifusome"—was ...

The brain’s cerebellum plays a key role in coordinating movement, balance, and cognition. Injury to the cerebellum can have a profound impact on basic motor skills, such as sitting, standing, and ...

Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510655, China Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, ...

Bispecific T cell engagers (TcEs) are immunotherapeutic drugs that trigger the destruction of cancer cells by linking T cells to cancer cells through specific surface molecules (antigens). We designed ...

Lymphatic muscle cells (LMCs) are indispensable for lymphatic vessel contraction, and their aberrant recruitment or absence is associated with both primary and secondary lymphedema. Despite their ...

It is well established that cellulose synthesis in higher plants requires three different but related cellulose synthase (CESA) isoforms. Here the authors provide convincing biochemical and cryo ...

The impact of circadian disruption on muscle health and aging has been uncovered. A research team at King’s College London (UK) has uncovered the intrinsic and extrinsic effects that circadian ...