When neuroscientists analyzed the exact properties of nerve connections in the brain, they made a startling observation: At a key connection, or synapse, messages are sent against the usual stream of ...

How do people think, feel, remember, and move? These processes rely on synaptic transmission, where chemical signals are passed between nerve cells using molecular structures called vesicles.

(1) A nerve impulse arrives. (2) This causes calcium ion channels to open, resulting in an influx of calcium ions in the terminal. (3) This causes synaptic vesicles to fuse with the terminal membrane, ...

The synaptotagmin protein family has been studied by neuroscientists for decades. However, most isoforms lack well-defined functions. Now, researchers have identified a crucial, presynaptic role for ...

Researchers at Fujita Health University and the Tokyo Metropolitan Institute of Medical Science have uncovered a previously overlooked form of brain abnormality linked to anxiety: excessive maturation ...

BIN1, one of the strongest genetic risk factors for late-onset Alzheimer’s disease, encodes a protein that dabbles in many cellular functions, taking a hand in Aβ production, tau propagation, and ...

A technical paper titled “3D Neuromorphic Hardware with Single Thin-Film Transistor Synapses Over Single Thin-Body Transistor Neurons by Monolithic Vertical Integration” was published by researchers ...

Transmission electron microscopy reveals the architecture of cells at nanometer resolution, but chemical fixation severely warps their native structure. The true ultrastructure of cells can be ...

Boost Neuroscience is a “stealth” biotech company that has developed a proprietary synapse network platform based on the work of Nobel Laureate Dr. Thomas Südhof, M.D. Boost was spun out of Stanford ...