Understanding the interaction between immune cells and cancer cells has important implications for cancer immunotherapies, including checkpoint inhibitor drugs and cell-based therapies, as well as ...

A US-Japanese trio on Monday won the Nobel Prize in Medicine for research into how the immune system is kept in check by identifying its "security guards," the Nobel jury said. The discoveries by Mary ...

Request permissions for this article. Cardiovascular Risk Factors and Brain Health Programme, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid ...

Summary: Alzheimer’s disease affects over 55 million people worldwide and has long been linked to toxic protein buildup and chronic inflammation in the brain. A new review shows that adaptive immune ...

Tom Anchordoquy receives funding for this work from the Nationals Institutes of Health through grant # RO1 CA289447. When the first cells appeared on Earth approximately 3.8 billion years ago, viruses ...

Having a robust enough immune system to live a longer life may come at the cost of chronic inflammation. Some immune cells undergo an inflammatory form of death that evolved to protect us from ...

Cancer immunotherapy has historically focused on harnessing the ability of T cells to recognize and attack cancer cells. Adaptive immune checkpoint inhibitors (ICIs) unleash tumor-infiltrating ...

Cancer immunotherapy, which primes the body's immune system to fight off tumors, has historically focused on harnessing T cells' natural ability to recognize and attack cancer cells. While this ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The crosstalk between Drosophila hemocytes and ...

Findings from St. Jude Children's Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life. The work stems ...

mRNA acts as blueprints that cells then base new proteins on. In the COVID-19 vaccines, the molecule contains instructions for a bit of the coronavirus; in the new cancer vaccine, it carries ...